Before that happened, President Donald Trump signed an executive order on January 23, 2017 to withdraw the United States from the agreement. In 2011, Secretary of State Hillary Clinton presented the strategic rationale for an Asia-focused trade deal. Protection of intellectual property. The agreement included detailed provisions on intellectual property, including the enforcement of patents, the extension of copyright conditions, and the protection of technology and trade secrets. These included controversial new protections for prescription drugs, including a new class of drugs known as biologics, pushed by the United States. Economists Peter A. Petri and Michael G. Plummer of the Peterson Institute for International Economics predict that the TPP would increase revenues in the United States by $131 billion a year, or 0.5 percent of GDP. U.S. exports are expected to grow by $357 billion a year, or 9.1 percent, as a result of the deal.
 However, two economists at Tufts University argue that Petri`s research is based on unrealistic assumptions such as full employment: lost jobs are immediately replaced in other industrial sectors.  According to Harvard economist Dani Rodrik, « Petri and Plummer assume that labor markets are so flexible that job losses in negatively affected parts of the economy are necessarily offset by job gains elsewhere. Unemployment is excluded from the outset – an integrated result of the model that TPP supporters often give.  Rodrik notes that « Petri Plummer`s model is directly rooted in decades of modelling academic trade, which makes a clear distinction between microeconomic effects (shaping the allocation of resources across sectors) and macroeconomic effects (relative to the overall level of demand and employment). In this tradition, trade liberalization is a microeconomic « shock » that affects the composition of employment, but not its overall level.  In October 2018, Japanese Prime Minister Shinzo Abe said that despite its geographical distance, the UK would be included in the CPTPP « with open arms, » indicating the potential of CPTPP member states to use the agreement as a global diplomatic framework in the coming years. « This is another wake-up call for the United States, » said Wendy Cutler, vice president of the Asia Society Policy Institute and a longtime U.S. trade representative who helped negotiate the TPP. « Now you have two mega-deals in the region, and both will lead to more integration between the members of these different blocs. » The TPP explicitly excludes the tobacco industry from the ISDS process.
 The split was in response to concerns about ISDS cases against anti-smoking laws, including Philip Morris v. Uruguay.  The ISDS tobacco exemption is a first for an international trade agreement.  On January 23, 2017, President Trump signed a presidential memorandum [Note 2] to remove the United States from the TPP.  U.S. Senator John McCain criticized the withdrawal, saying, « It will send a troubling signal of U.S. withdrawal in the Asia-Pacific region at a time when we can least afford it. »  U.S. Senator Bernie Sanders welcomed the decision, saying, « Over the past 30 years, we have had a number of trade agreements … which have cost us millions of decently paid jobs and created a « race to the bottom » that has lowered the wages of American workers.
 A September 2016 report by the Institute for Agriculture and Trade Policy (IATP) predicts that « if countries take action to protect the climate, conflicts between trade rules and climate goals will intensify. » :1 The report goes on to say that trade agreements such as the TPP set far-reaching rules for the economy and government policies, thereby expanding trade, often in the extractive sectors, and protecting businesses and financial corporations from future measures to stabilize the climate.  In a 2018 study on general foreign trade, researchers found that a significant majority of the United States. .